Avigdor Scherz Selected Research

palladium-bacteriopheophorbide

1/2021	Neoadjuvant vascular-targeted photodynamic therapy improves survival and reduces recurrence and progression in a mouse model of urothelial cancer.
1/2017	Bombesin Antagonist-Based Radiotherapy of Prostate Cancer Combined with WST-11 Vascular Targeted Photodynamic Therapy.
10/2013	TOOKAD(®) Soluble vascular-targeted photodynamic (VTP) therapy: determination of optimal treatment conditions and assessment of effects in patients with localised prostate cancer.
4/2010	Permanent occlusion of feeding arteries and draining veins in solid mouse tumors by vascular targeted photodynamic therapy (VTP) with Tookad.
4/2009	Treatment planning and dose analysis for interstitial photodynamic therapy of prostate cancer.
8/2008	Vascular-targeted photodynamic therapy (padoporfin, WST09) for recurrent prostate cancer after failure of external beam radiotherapy: a study of escalating light doses.
5/2005	The microenvironment effect on the generation of reactive oxygen species by Pd-bacteriopheophorbide.
6/2004	Perfusion, oxygenation status and growth of experimental tumors upon photodynamic therapy with Pd-bacteriopheophorbide.
5/2004	Photodynamic therapy of established prostatic adenocarcinoma with TOOKAD: a biphasic apparent diffusion coefficient change as potential early MRI response marker.
11/2003	Bypass of tumor drug resistance by antivascular therapy.

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Avigdor Scherz Research Topics

Disease

36	Neoplasms (Cancer) 11/2021 - 05/2002
15	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 10/2002
11	Necrosis 01/2017 - 05/2002
5	Carcinoma (Carcinomatosis) 01/2019 - 11/2003
3	Adenocarcinoma 11/2021 - 05/2004
3	Pancreatic Neoplasms (Pancreatic Cancer) 11/2021 - 01/2020
3	Neoplasm Metastasis (Metastasis) 01/2021 - 05/2002
3	Phototoxic Dermatitis (Phototoxicity) 01/2020 - 03/2005
3	Inflammation (Inflammations) 01/2015 - 05/2002
3	Melanoma (Melanoma, Malignant) 07/2005 - 03/2005
3	Hypoxia (Hypoxemia) 10/2004 - 05/2003
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2018 - 01/2018
2	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 11/2013 - 07/2011
2	Macular Degeneration (Age-Related Maculopathy) 01/2009 - 10/2003
2	Photosensitivity Disorders (Photodermatitis) 10/2004 - 10/2003
1	Pancreatitis 01/2021
1	Carcinogenesis 01/2018
1	Body Weight (Weight, Body) 10/2016
1	Urinary Retention 11/2013
1	Pathologic Dilatation (Ectasia) 09/2012
1	Keratoconus 09/2012
1	Intussusception 07/2011
1	Breast Neoplasms (Breast Cancer) 01/2010
1	Choroidal Neovascularization 04/2008
1	Sarcoma (Soft Tissue Sarcoma) 06/2004
1	Small Cell Carcinoma 05/2003

Drug/Important Bio-Agent (IBA)

14	palladium-bacteriopheophorbideIBA 01/2021 - 05/2002
14	padeliporfinIBA 01/2021 - 10/2004
11	1-phenyl-3,3-dimethyltriazene (PDT)IBA 11/2020 - 05/2002
9	BacteriochlorophyllsIBA 01/2017 - 05/2003
8	Photosensitizing Agents (Photosensitizers)IBA 01/2018 - 10/2002
3	Lactic Acid (Lactate)FDA LinkGeneric 11/2021 - 01/2021
3	Pharmaceutical PreparationsIBA 01/2017 - 10/2003
2	DeuteriumIBA 11/2021 - 01/2021
2	Glucose (Dextrose)FDA LinkGeneric 11/2021 - 01/2021
2	TESIBA 11/2021 - 01/2020
2	AntigensIBA 01/2021 - 05/2011
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2015
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 10/2004
2	NitrogenIBA 01/2018 - 01/2017
2	Oxygen (Dioxygen)IBA 01/2017 - 01/2009
2	Serum AlbuminIBA 01/2010 - 03/2005
2	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2004 - 10/2003
1	Eosine Yellowish-(YS) (Eosin)IBA 01/2021
1	Immune Checkpoint InhibitorsIBA 01/2021
1	gallium 68 PSMA-11IBA 01/2021
1	Hematoxylin (Haematoxylon)IBA 01/2021
1	Pyruvic Acid (Pyruvate)IBA 01/2021
1	Biological ProductsIBA 01/2021
1	ChlorophyllIBA 11/2020
1	Immunoglobulins (Immunoglobulin)IBA 01/2020
1	Riboflavin (Vitamin B2)FDA LinkGeneric 01/2020
1	pyrimidineIBA 01/2018
1	acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamide FDA Link 01/2018
1	AndrogensIBA 01/2018
1	AntibodiesIBA 01/2018
1	Aspartate CarbamoyltransferaseIBA 01/2018
1	Carbamyl Phosphate (Carbamoyl Phosphate)IBA 01/2018
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 01/2018
1	EnzymesIBA 01/2018
1	Free RadicalsIBA 01/2018
1	PalladiumIBA 01/2017
1	Radioisotopes (Radionuclides)IBA 01/2017
1	Peptides (Polypeptides)IBA 01/2017
1	Bombesin Receptors (Bombesin Receptor)IBA 01/2017
1	RadiopharmaceuticalsIBA 01/2017
1	BombesinIBA 01/2017
1	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA 01/2017
1	CollagenIBA 10/2016
1	CathepsinsIBA 01/2015
1	Integrin alphaVbeta3IBA 01/2010
1	LigandsIBA 01/2010
1	hydroxide ionIBA 07/2009
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2009
1	LuciferasesIBA 09/2008
1	LuciferinsIBA 09/2008
1	Blood Proteins (Serum Proteins)IBA 07/2005
1	Indicators and Reagents (Reagents)IBA 05/2005
1	Superoxides (Superoxide)IBA 05/2005
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 05/2005
1	Hydroxyl RadicalIBA 05/2005
1	Singlet OxygenIBA 05/2005
1	SolventsIBA 05/2005
1	PlacebosIBA 06/2004
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 11/2003
1	Chromogranin AIBA 05/2003

Therapy/Procedure

30	Photochemotherapy (Photodynamic Therapy) 01/2021 - 05/2002
19	Therapeutics 01/2021 - 05/2002
4	Immunotherapy 01/2021 - 05/2011
3	Aftercare (After-Treatment) 01/2018 - 06/2004
3	Radiotherapy 01/2017 - 08/2008
2	Lasers (Laser) 01/2016 - 06/2004
2	Drug Therapy (Chemotherapy) 05/2011 - 11/2003
1	Corneal Cross-Linking 01/2020
1	Phototherapy (Light Therapy) 10/2018
1	Intravenous Infusions 10/2016
1	Optical Fibers 10/2016
1	Precision Medicine 01/2015
1	Refractive Surgical Procedures 09/2012
1	Ligation 01/2010